Diabetes 3: Insulin and Official Launch

Classes of insulin and different treatment regimens are discussed in the third episode of a 3-part series on diabetes. This episode also marks the conclusion of our coverage of the “Big Three” of modern medicine (hypertension, dyslipidemia, and diabetes), and with it, we make an official announcement of the launch of the Family Pharm Podcast to the world (aka Facebook)!


Class Drug Onset Peak Duration
Very Rapid-acting Insulin Analogues insulin aspart
10–15 min 60–90 min 4–5 h
insulin glulisine
insulin lispro
Rapid-acting Insulin insulin regular
(Humulin R, Novolin ge Toronto)
30–60 min 2–4 h 5–8 h
Intermediate-acting Insulin insulin NPH
(Humulin N, Novolin ge NPH)
1–2 h 5–8 h 14–18 h
Long-acting Insulin Analogues insulin detemir
1.5 h Flat, no discernible peak 24 h
insulin glargine
Mixed (regular/NPH) Human Insulin insulin regular/insulin NPH
Humulin 30/70,
Novolin ge 30/70, 40/60, 50/50
Combination of individual components
Mixed Insulin Analogues insulin lispro/lispro protamine
Humalog Mix25, Humalog Mix50
10–15 min Not available Not available
Mixed Insulin Analogues insulin aspart/aspart protamine
NovoMix 30
10–15 min 60–90 min 15–18 h

Classes of insulin preparations. Adapted from Therapeutic Choices 6th edition.

CDA guideline on insulin for Type 1 diabetes, including description of basal-bolus regimen by carb counting:

Examples of insulin regimens from CDA:

Self monitoring: